ACKR2 Mouse anti-Human, Clone: 1A3A2, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 600461IG150UL

Catalog No. 50-173-6205

Description

This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Specifications

• Antigen: ACKR2
• Classification: Monoclonal
• Concentration: 0.83 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: O00590
• Gene Symbols: ACKR2
• Immunogen: ACKR2 Fusion Protein Ag1941
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: 1A3A2
• Conjugate: Unconjugated
• Gene: ACKR2
• Gene Alias: ACKR2, C C chemokine receptor D6, CCBP2, CCR10, CCR9, chemokine binding protein 2, Chemokine binding protein D6, Chemokine receptor CCR 10, Chemokine receptor CCR 9, CMKBR9, D6, hD6
• Host Species: Mouse
• Purification Method: Caprylic Acid Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 1238
• Content And Storage: -20°C
• Form: Liquid