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Invitrogen™ Acrosomal Vesicle Protein Monoclonal Antibody (Ds-2)
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Catalog No. 01675972
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100 μg
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Catalog No. Quantity
01-675-972 100 μg
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Catalog No. 01-675-972 Supplier Invitrogen™ Supplier No. MA119208
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Description

Mouse Monoclonal Antibody

This antibody reacts with canine intra-acrosomal sperm protein (92 and 42 kDa), a testis-specific acrosomal vesicle protein 1 associated with the acrosomal membranes and matrix of the mature sperm. Immunocytochemistry: Membrane permeabilization (acetone) is essential.

This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Acrosomal Vesicle Protein
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone Ds-2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene ACRV1
Gene Accession No. 0
Gene Alias acrosomal protein SP-10; Acrosomal vesicle protein 1; Acrv1; D11S4365; Msa63; MSA-63; rSP10; Sp10; SP-10; SPACA2; sperm membrane protein; sperm protein 10
Gene Symbols ACRV1
Host Species Mouse
Immunogen Freshly ejaculated dog sperms.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 607249
Target Species Canine
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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