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ACT 335827, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
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1354039-86-3
C31H38N2O5
518.654
HXHOBPVRRPCTLG-SETSBSEESA-N
compound 9 pmid: 23589487,2r-2-1s-1-3,4-dimethoxyphenyl methyl-6,7-dimethoxy-3,4-dihydro-1h-isoquinolin-2-yl-2-phenyl-n-propan-2-ylacetamide,ar,1s-1-3,4-dimethoxyphenyl methyl-3,4-dihydro-6,7-dimethoxy-n-1-methylethyl-a-phenyl-2 1h-isoquinolineacetamide,r-2-s-1-3,4-dimethoxybenzyl-6,7-dimethoxy-3,4-dihydroisoquinolin-2 1h-yl-n-isopropyl-2-phenylacetamide
54765113
(2R)-2-[(1S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-2-phenyl-N-propan-2-ylacetamide
CC(C)NC(=O)C(C1=CC=CC=C1)N2CCC3=CC(=C(C=C3C2CC4=CC(=C(C=C4)OC)OC)OC)OC
This item is not returnable. View return policy
1354039-86-3
C31H38N2O5
518.654
HXHOBPVRRPCTLG-SETSBSEESA-N
compound 9 pmid: 23589487,2r-2-1s-1-3,4-dimethoxyphenyl methyl-6,7-dimethoxy-3,4-dihydro-1h-isoquinolin-2-yl-2-phenyl-n-propan-2-ylacetamide,ar,1s-1-3,4-dimethoxyphenyl methyl-3,4-dihydro-6,7-dimethoxy-n-1-methylethyl-a-phenyl-2 1h-isoquinolineacetamide,r-2-s-1-3,4-dimethoxybenzyl-6,7-dimethoxy-3,4-dihydroisoquinolin-2 1h-yl-n-isopropyl-2-phenylacetamide
54765113
(2R)-2-[(1S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-2-phenyl-N-propan-2-ylacetamide
CC(C)NC(=O)C(C1=CC=CC=C1)N2CCC3=CC(=C(C=C3C2CC4=CC(=C(C=C4)OC)OC)OC)OC

Potent and selective OX1 antagonist

Potent and selective orexin OX1 receptor antagonist (Kb values are 41 and 560 nM for OX1 and OX2 receptors respectively). Elicits anxiolytic effects in vivo. Brain penetrant and orally available.

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Quantity 10mg
Formula Weight 518.64
Chemical Name or Material ACT 335827

Recommended Storage : Store at -20°C