Tocris ACT 462206
Potent, dual orexin receptor antagonist
Manufacturer: Tocris 5319/50
DescriptionPotent, dual orexin receptor antagonist (IC50 values are 11 and 60nM for OX2 and OX1 receptors respectively). Exhibits anxiolytic-like properties in vivo. Brain penetrant.
- Chemical Name: (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide
- Formula: C20H24N2O4S
- CAS Number: 1361321-96-1
- Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
- Purity: >99
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