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ACTA2/smooth muscle actin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 50556990 Shop All Proteintech Group Inc Products
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50-556-990 150 μL
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Catalog No. 50-556-990 Supplier Proteintech Group Inc Supplier No. 143951AP150UL
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Rabbit Polyclonal Antibody

This antibody may cross-react with other isoforms of actins.

Among the six actin isoforms described in mammals, two are found in virtually all cells (b- and g-cytoplasmic), two are detected in smooth muscle cells (a- and g-smooth muscle) and two are present in striated muscles, one predomitly in skeletal (a-skeletal) and one in cardiac (a-cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus and the sequences of each of them are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown to appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases.

Specifications

Antigen ACTA2/smooth muscle actin
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ACTA2
Gene Accession No. P62736, P62737, P62738
Gene Alias a SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, Actin, aortic smooth muscle, Actin, aortic smooth muscle Actin, ACTSA, ACTVS, Alpha actin 2, Alpha SMA, a-SMA, alpha SMA
Gene Symbols ACTA2
Host Species Rabbit
Immunogen ACTA2/smooth muscle actin Fusion Protein Ag5886
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11475, 59, 81633
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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