ACTA2/smooth muscle actin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 143951AP150UL

Catalog No. 50-556-990

Description

This antibody may cross-react with other isoforms of actins.

Among the six actin isoforms described in mammals, two are found in virtually all cells (b- and g-cytoplasmic), two are detected in smooth muscle cells (a- and g-smooth muscle) and two are present in striated muscles, one predomitly in skeletal (a-skeletal) and one in cardiac (a-cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus and the sequences of each of them are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown to appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases.

Specifications

• Antigen: ACTA2/smooth muscle actin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACTA2
• Gene Alias: a SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, Actin, aortic smooth muscle, Actin, aortic smooth muscle Actin, ACTSA, ACTVS, Alpha actin 2, Alpha SMA, a-SMA, alpha SMA
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11475, 59, 81633
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
• Concentration: 0.29 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P62736, P62737, P62738
• Gene Symbols: ACTA2
• Immunogen: ACTA2/smooth muscle actin Fusion Protein Ag5886
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG