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Actinomycin D (1 mg/ml, DMSO)

Catalog No. AAJ67160XF
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Description

CAS: 50-76-0 | C62H86N12O16 | 1255.438 g/mol

Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm?s tumor and the sarcomas.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm′s tumor and the sarcomas.

Solubility
Soluble in acetonitrilie or acetone at 10 mg/mL and in DMSO at a minimum of 1 mg/mL, slightly soluble in water.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 50-76-0
Molecular Formula C62H86N12O16
Molecular Weight (g/mol) 1255.438
MDL Number MFCD00005033
InChI Key RJURFGZVJUQBHK-HUZQGMAJSA-N
Synonym Dactinomycin; Actinomycin C1
PubChem CID 131954673
IUPAC Name 2-amino-4,6-dimethyl-3-oxo-1-N-[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-9-N-[(3R,6S,7R,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,
SMILES CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C

Specifications

Type Actinomycin D
Physical Form Liquid
Quantity 1 mL
Solubility Information Soluble in acetonitrilie or acetone at 10mg/mL and in DMSO at a minimum of 1mg/mL,slightly soluble in water.
Chemical Name or Material Actinomycin D, 1mg/mL in DMSO, sterile-filtered

Safety and Handling

Hazard Category H227
Hazard Statement GHS H Statement
H227
Combustible liquid.
Precautionary Statement P210-P280-P370+P378q-P501c
EINECSNumber 200-063-6
RTECSNumber AU1575000
TSCA No
storageNote1 -30° to -10°C
Recommended Storage Store at -20°C
SDS

RUO – Research Use Only

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