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Invitrogen™ ACVR2A Monoclonal Antibody (A7C8)
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Catalog No. FEMA550611
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100 μL
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FEMA550611 100 μL
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Catalog No. FEMA550611 Supplier Invitrogen™ Supplier No. MA550611
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Description

Mouse Monoclonal Antibody

Positive control: K562 cell lysate, HepG2 cell lysate. Predicted band size: 58 kDa Subcellular Location: Membrane.

Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases. ACVR2A is involved in the activin and myostatin signaling pathway. (ACVR2A Aliases: ACVR2, ACTRII). These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2A
Applications Western Blot
Classification Monoclonal
Clone A7C8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene ACVR2A
Gene Accession No. P27037
Gene Alias activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor
Gene Symbols ACVR2A
Host Species Mouse
Immunogen Synthetic peptide within Human ACVR2A aa 464-513/513.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 92
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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