Invitrogen™ ACVR2B Monoclonal Antibody (A5H6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA542556

Catalog No. PIMA542556

Description

Positive Control: Hela cell lysates. Subcellular Location: Cell membrane.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.

Specifications

• Antigen: ACVR2B
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P27040, P38445, Q13705
• Gene Symbols: ACVR2B, acvr2ba
• Immunogen: Synthetic peptide within human ACVR2B aa 331-380/512.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Zebrafish
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: A5H6
• Conjugate: Unconjugated
• Gene: ACVR2B
• Gene Alias: activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 11481, 25366, 30457, 93
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov