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Invitrogen™ ACVR2B Monoclonal Antibody (A5H7)
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Catalog No. PIMA542557
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100 μL
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PIMA542557 100 μL
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Catalog No. PIMA542557 Supplier Invitrogen™ Supplier No. MA542557
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Description

Mouse Monoclonal Antibody

Positive Control: Hela cell lysates. Subcellular Location: Cell membrane.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2B
Applications Western Blot
Classification Monoclonal
Clone A5H7
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene ACVR2B
Gene Accession No. P27040, P38445, Q13705
Gene Alias activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Gene Symbols ACVR2B, acvr2ba
Host Species Mouse
Immunogen Synthetic peptide within human ACVR2B aa 331-380.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11481, 25366, 30457, 93
Target Species Human, Mouse, Rat, Zebrafish
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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