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Invitrogen™ ACVR2B Polyclonal Antibody
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Catalog No. PIPA528231
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PIPA528231 100 μL
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Catalog No. PIPA528231 Supplier Invitrogen™ Supplier No. PA528231
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG, SK-N-SH, IMR-32, SK-N-AS, mosue cerebellum, mouse testis, ACVR2B-transfected 293T. Predicted reactivity: Mouse (99%), Rat (99%), Pig (100%), Chicken (89%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene ACVR2B
Gene Accession No. P27040, Q13705
Gene Alias activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Gene Symbols ACVR2B
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Activin Receptor Type IIB. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11481, 93
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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