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Acyclovir, Tocris Bioscience™

Catalog No. 251350
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50 mg
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Catalog No. Quantity
25-135-0 50 mg
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Catalog No. 25-135-0 Supplier R&D Systems Supplier No. 2513/50
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Description

Inhibits viral DNA polymerase; antiherpetic agent

Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC50 values are 0.85 and 0.86 μM respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).

Chemical Identifiers

CAS 59277-89-3
Molecular Formula C8H11N5O3
Molecular Weight (g/mol) 225.21
MDL Number MFCD00057880
InChI Key MKUXAQIIEYXACX-UHFFFAOYSA-N
Synonym acyclovir, aciclovir, acycloguanosine, zovirax, vipral, virorax, wellcome-248u, 9-2-hydroxyethoxy methyl guanine, zovir, aciclovirum
PubChem CID 2022
ChEBI CHEBI:2453
IUPAC Name 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-1H-purin-6-one
SMILES NC1=NC2=C(N=CN2COCCO)C(=O)N1

Specifications

Quantity 50 mg
Formula Weight 225.21
Percent Purity >99%
Chemical Name or Material Acyclovir

Safety and Handling

Recommended Storage Store at Room Temperature
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