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Vector Biolabs The Adenovirus Co Cre Recombinase Adenovirus (Ad-CMV-iCre)
Supplier: Vector Biolabs The Adenovirus Co 1045
This Cre recombinant adenovirus expresses Cre recombinase, a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.This adenovirus expresses a codon improved Cre (iCre) under a CMV promoter.
Check out this instruction video on using our adenovirus Cre to knockout LoxP flanked gene in primary mouse embryonic fibroblasts (MEF).
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