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Invitrogen™ ADAM15 Polyclonal Antibody
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Catalog No. PIPA527459
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100 μL
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PIPA527459 100 μL
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Catalog No. PIPA527459 Supplier Invitrogen™ Supplier No. PA527459
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, HepG2, Molt-4, NIH-3T3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADAM15
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.347 mg/mL
Conjugate Unconjugated
Formulation PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene Adam15
Gene Accession No. O88839, Q13444, Q9QYV0
Gene Alias a disintegrin and metallopeptidase domain 15 (metargidin); a disintegrin and metalloprotease domain 15 (metargidin); a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 15; a disintegrin and metalloproteinase domain 15 (metargidin); AD56; ADAM; ADAM 15; ADAM metallopeptidase domain 15; Adam15; ADAMs; CRII-7; disintegrin and metalloprotease 15; disintegrin and metalloproteinase domain-containing protein 15; Mdc15; MDC-15; metalloendopeptidases; Metalloprotease RGD disintegrin protein; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15; metargidin; tMDC VI; tMDCVI
Gene Symbols Adam15
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human ADAM15. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11490, 57025, 8751
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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