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ADAMTS13 Goat anti-Human, Polyclonal, Bethyl Laboratories
Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Gorilla and Chimpanzee
ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
Specifications
Specifications
| Antigen | ADAMTS13 |
| Applications | Immunoprecipitation |
| Classification | Polyclonal |
| Concentration | 1 mg/ml |
| Conjugate | Unconjugated |
| Formulation | phosphate, tris citrate with 0.09% sodium azide; pH 7-8 |
| Gene | ADAMTS13 |
| Gene Accession No. | Q76LX8 |
| Gene Alias | von Willebrand factor-cleaving protease; vWF-cleaving protease; vWF-CP; A disintegrin and metalloproteinase with thrombospondin motifs 13; ADAMTS-13; ADAM-TS 13; ADAM-TS13; ADAMTS13; C9orf8 |
| Gene Symbols | ADAMTS13 |
| Show More |
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