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Invitrogen™ ADAMTS5 Polyclonal Antibody
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Catalog No. PIPA527165
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100 μL
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PIPA527165 100 μL
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Catalog No. PIPA527165 Supplier Invitrogen™ Supplier No. PA527165
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HCT116, MCF-7, JC. Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ADAMTS5, also known as Implantin or Aggrecanase 2, is a member of the larger family of ADAMs (A Disintegrin And Metalloproteinase) metalloproteinases containing thrombospondin (TS) repeats. ADAMTS5 (A Disintegrin And Metalloproteinase with Thrombospondin-5 motif) was first described as ADAMTS5, a protein elevated in mice during the peri-implantion period. At the same time, another group identified Aggrecanase 11, a protein elevated in arthritic synovium. The name was later changed to ADAMTS5. ADAMTS5 is expressed in human and mouse. It has been found in heart, lung, cervix, uterus, ovary, brain, cartilage, and numerous other tissues, as well as chondroblastoma cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADAMTS5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene ADAMTS5
Gene Accession No. Q9R001, Q9UNA0
Gene Alias 9530092O11Rik; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 11; A disintegrin and metalloproteinase with thrombospondin motifs 5; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; ADAMs; ADAM-TS 11; ADAM-TS 5; ADAMTS family member; ADAMTS1; ADAMTS11; ADAMTS-11; ADAMTS5; ADAM-TS5; ADAMTS-5; ADMP2; ADMP-2; Aggrecanase 2; Aggrecanase-2; AI481094; ASMP-2; Implantin; metalloendopeptidases
Gene Symbols ADAMTS5
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ADAMTS5. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11096, 23794
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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