Invitrogen™ ADAMTS5 Polyclonal Antibody

Catalog No.	Quantity
PA11742	100 μg

Catalog No. PA11742 Supplier Invitrogen™ Supplier No. PA11742

Description

Rabbit Polyclonal Antibody

PA1-1742 detects ADAMTS5 in human samples. PA1-1742 has been successfully used in Western blot procedures. In Western blot analysis of JJ012 cells this antibody detects a ~64 kDa protein representing ADAMTS5. The PA1-1742 immunogen is a synthetic peptide corresponding to residues C I(442) L T S I D A S K P(451) of human ADAMTS5.

ADAMTS5, also known as Implantin or Aggrecanase 2, is a member of the larger family of ADAMs (A Disintegrin And Metalloproteinase) metalloproteinases containing thrombospondin (TS) repeats. ADAMTS5 (A Disintegrin And Metalloproteinase with Thrombospondin-5 motif) was first described as ADAMTS5, a protein elevated in mice during the peri-implantion period. At the same time, another group identified Aggrecanase 11, a protein elevated in arthritic synovium. The name was later changed to ADAMTS5. ADAMTS5 is expressed in human and mouse. It has been found in heart, lung, cervix, uterus, ovary, brain, cartilage, and numerous other tissues, as well as chondroblastoma cell lines.

Specifications

• Antigen: ADAMTS5
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene: ADAMTS5
• Gene Accession No.: Q9UNA0
• Gene Alias: 9530092O11Rik; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 11; A disintegrin and metalloproteinase with thrombospondin motifs 5; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; ADAMs; ADAM-TS 11; ADAM-TS 5; ADAMTS family member; ADAMTS1; ADAMTS11; ADAMTS-11; ADAMTS5; ADAM-TS5; ADAMTS-5; ADMP2; ADMP-2; Aggrecanase 2; Aggrecanase-2; AI481094; ASMP-2; Implantin; metalloendopeptidases
• Gene Symbols: ADAMTS5
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to residues C I(442) L T S I D A S K P(451) of human ADAMTS5.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11096
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG