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Invitrogen™ ADAMTSL2 Polyclonal Antibody
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Catalog No. PIPA521414
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100 μL
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PIPA521414 100 μL
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Catalog No. PIPA521414 Supplier Invitrogen™ Supplier No. PA521414
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: H1299. Predicted reactivity: Mouse (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ADAMTSL2, or A Disintegrin And Metalloproteinase with Thrombospondin Motifs Like 2, is a gene that codes for a secreted glycoprotein involved in the regulation of extracellular matrix (ECM) and associated proteases. The gene, initially identified by the Kazusa DNA Research Institute, plays a crucial role in various biological processes including ECM remodeling. Mutations or alterations in ADAMTSL2 are implicated in multiple diseases, including genetic disorders like geleophysic dysplasia and cancer. Its expression levels and genetic variants have been correlated with cancer progression, immune cell infiltration in tumors, and other pathological conditions like non-alcoholic steatohepatitis (NASH). ADAMTSL2 is a potential biomarker for disease prognosis and therapeutic targeting due to its significant role in ECM dynamics and disease pathology.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADAMTSL2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7
Gene ADAMTSL2
Gene Accession No. Q7TSK7, Q86TH1
Gene Alias a disintegrin and metalloproteinase; A930008K15Rik; ADAM; ADAMs; ADAMTS like 2; Adamtsl2; ADAMTSL-2; ADAMTS-like 2; ADAMTS-like protein 2; GPHYSD1; Kiaa0605; metalloendopeptidases; RGD1305459; Tcp1; TCP-1; TSP1-repeat-containing protein 1; TSP1-repeats containing protein; TSP1-repeats-containing protein 1
Gene Symbols ADAMTSL2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human ADAMTSL2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 77794, 9719
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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