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Invitrogen™ ADFP Recombinant Rabbit Monoclonal Antibody (JA31-81)
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Catalog No. PIMA532664
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PIMA532664 100 μL
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Catalog No. PIMA532664 Supplier Invitrogen™ Supplier No. MA532664
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADFP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JA31-81
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% Glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene Plin2
Gene Accession No. P43883, Q99541
Gene Alias AA407157; Adfp; Adipophilin; adipose differentiation related protein; adipose differentiation-related protein; ADPH; Adrp; ADRP antibody; MGC10598; perilipin 2; perilipin-2; Plin2
Gene Symbols Plin2
Host Species Rabbit
Immunogen Synthetic peptide within Human ADFP aa 18-67.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11520, 123, 298199
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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