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Invitrogen™ ADSL Recombinant Rabbit Monoclonal Antibody (001), Invitrogen™

Catalog No. PIMA543474
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PIMA543474 50 μL
PIMA543054 100 μL
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Catalog No. PIMA543474 Supplier Invitrogen™ Supplier No. MA543474
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: Human ADSL/Adenylosuccinate Lyase

ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that is involved in both purine biosynthesis and in the formation of adenosine monophosphate (AMP) from inosine monophosphate. Expressed ubiquitously, ADSL catalyzes two key reactions in AMP biosynthesis, namely the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and the subsequent removal of fumarate from adenylosuccinate to yield AMP. Defects in the gene encoding ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency), an autosomal recessive disorder characterized by epilepsy, growth retardation and muscular wasting. Multiple isoforms of ADSL exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADSL
Applications ELISA
Classification Recombinant Monoclonal
Clone 001
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Adsl
Gene Accession No. P30566
Gene Alias 2510006M18Rik; Adenylosuccinase; adenylosuccinate lyase; adenylosuccinate lyase 1; Adl; Adsl; AMPS; argininosuccinase; argininosuccinate lyase; Arginosuccinase; ASAL; ASase; ASL; null; test; unnamed protein product
Gene Symbols Adsl
Host Species Rabbit
Immunogen Recombinant Human ADSL/Adenylosuccinate Lyase protein.
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 158
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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