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Tocris Bioscience™ ADU-S100 disodium salt
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Catalog No. 7706735U
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Quantity:
73.5 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

STING agonist

ADU-S100 disodium salt is a STING agonist. It induces CD8+ T-cell mediated antitumor immunity in a rat esophageal adenocarcinoma model. In mouse tumor models, the compound induces tumor regression and a potent antitumor immune response. ADU-S100 disodium salt induces phosphorylation of TBK1 and IRF3 in murine bone marrow macrophages.

Specifications

Chemical Name or Material [P(R)]-5'-O-[(R)-Hydroxymercaptophosphinyl]-P-thioadenylyl-(2'→5')-adenosine cyclic nucleotide disodium
CAS 1638750-95-4
Quantity 73.5 μg
Target STING Agonists
Molecular Formula C20H22N10Na2O10P2S2
Purity 95%
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