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Invitrogen™ AFF4 Monoclonal Antibody (8G12)
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Catalog No. PIMA549267
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Quantity:
100 μg
Catalog No. Quantity
PIMA549267 100 μg
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Catalog No. PIMA549267

Supplier: Invitrogen™ MA549267

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Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Immunogen sequence is identical to the related mouse sequence. Positive Control - WB: human HELA whole cell, human HEPG2 whole cell, human CACO-2 whole cell, human HEK293 whole cell, human MDA-MB-453 whole cell, human PANC-1 whole cell, human SW620 whole cell. Flow: 293T cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AFF4
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone 8G12
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene AFF4
Gene Accession No. Q9UHB7
Gene Alias AF4/FMR2 family member 4; AF4/FMR2 family, member 4; AF5Q31; Aff4; Alf4; ALL1 fused gene from 5q31; ALL1-fused gene from chromosome 5q31 protein; CHOPS; HSPC092; Laf4l; LOW QUALITY PROTEIN: AF4/FMR2 family member 4; major CDK9 elongation factor-associated protein; MCEF; Protein AF-5q31; RA_m002_jsmFBA6Br
Gene Symbols AFF4
Host Species Mouse
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human AFF4 (6-53aa RNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQ).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27125
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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