Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA514666

Invitrogen™ AFP Monoclonal Antibody (P5B8)
GREENER_CHOICE

Catalog No. PIMA514666
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA514666 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA514666 Supplier Invitrogen™ Supplier No. MA514666
Only null left
Add to Cart
Edge
Add to Cart

Description

Mouse Monoclonal Antibody

MA5-14666 can be used for immunofluorescence analysis of AFP in the endoderm derived from human embryonic stem cells. By Western blot, MA5-14666 detects endogenous AFP protein in the early hepatocyte-like cells derived from human embryonic stem cells. Product MA514666 is a smaller package size of MIA1305 (formerly sold as a Seradyn product).

AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AFP
Applications ELISA, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone P5B8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.01M potassium phosphate with 1 mg/mL BSA, 0.135M NaCl, 2.5mM KCl and 0.05% sodium azide
Gene AFP
Gene Accession No. P02771
Gene Alias a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; α fetoglobulin; α fetoprotein
Gene Symbols AFP
Host Species Mouse
Immunogen Purified AFP from Cord Blood.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 174
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.