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AFP Polyclonal Antibody, Invitrogen™

Catalog No. PIPA516658
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500 μL
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PIPA516658 500 μL
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Catalog No. PIPA516658 Supplier Thermo Scientific Supplier No. PA516658
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Description

Rabbit Polyclonal Antibody

PA5-16658 targets Alpha Fetoprotein in IHC (P) and WB applications and shows reactivity with Human, Ovine, and Porcine samples. The PA5-16658 immunogen is purified alpha-fetoprotein.

AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AFP
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene AFP
Gene Accession No. P02771, Q8MJ76
Gene Alias a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Gene Symbols AFP
Host Species Rabbit
Immunogen Purified alpha-fetoprotein
Purification Method purified
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101103646, 174, 397586
Target Species Human, Ovine, Pig
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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