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Apexbio Technology LLC AGK7 304896-21-7 1mg
SDP

Supplier:  Apexbio Technology LLC C57091

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AGK7 (CAS 304896-21-7) is a small molecule used as an inactive control compound for AGK2 a selective inhibitor of the NAD -dependent deacetylase SIRT2 While AGK2 potently inhibits SIRT2 activity (IC50 3 5 M) and increases cellular acetylated tubulin levels AGK7 lacks this inhibitory effect Notably in cellular models AGK2 but not AGK7 reduces -synuclein-mediated toxicity and modulates protein aggregation AGK7 serves as a specificity control in studies investigating the role of SIRT2 in cellular processes such as cell cycle regulation neurodegeneration and epigenetic modification

Catalog No. 50-000-92788


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