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Invitrogen™ AGR2 Polyclonal Antibody

Catalog No. PI720305
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100 μg
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PI720305 100 μg
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Catalog No. PI720305 Supplier Invitrogen™ Supplier No. 720305
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Description

Rabbit Polyclonal Antibody

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature. This antibody is predicted to react with Monkey, Dog, Cat and Bovine.

AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).
TRUSTED_SUSTAINABILITY

Specifications

Antigen AGR2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4
Gene Agr2
Gene Accession No. O88312, O95994
Gene Alias AG2; AG-2; AGR2; agr2 protein; Agr2h; AII; AII type II arginase; anterior gradient 2; anterior gradient 2 homolog; anterior gradient 2 homologue; anterior gradient 2, protein disulphide isomerase family member; anterior gradient homolog 2; anterior gradient protein 2 homolog; ARG2; arginase 2; arginase II; arginase type II; arginase, type II; arginase-2, mitochondrial; AU022422; epididymis secretory protein Li 116; Gob4; Gob-4; HAG-2; HEL-S-116; HPC8; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; mAG-2; nonhepatic arginase; Non-hepatic arginase; PDIA17; protein disulfide isomerase family A, member 17; protein Gob-4; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; Type II arginase; UNQ515/PRO1030; XAG-2
Gene Symbols Agr2
Host Species Rabbit
Immunogen Peptides corresponding to Human AGR2 (31-44, 164-175).
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10551, 23795, 298961
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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