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Invitrogen™ AHA1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA578743
Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human MCF-7 whole cell, human PC-3 whole cell, human A549 whole cell, monkey COS-7 whole cell.
Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155). [UniProt].
Specifications
AHA1 | |
Polyclonal | |
Unconjugated | |
Ahsa1 | |
Activator of 90 kDa heat shock protein ATPase homolog 1; activator of Hsp90 ATPase activity 1; Activator of Hsp90 ATPase protein 1; Aha 1; AHA1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); AHA1, activator of heat shock protein ATPase 1; AHA1, activator of heat shock protein ATPase homolog 1; Aha1p; AHSA 1; Ahsa1; BC023857; C14orf3; hAha1; Hsp90 co-chaperone AHA1; HSPC322; p38; SHSA1; YD8142.16; YD8142B.06; YDR214W | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
10598 | |
-20°C | |
Lyophilized |
ELISA, Western Blot | |
500 μg/mL | |
PBS with 4mg trehalose and 0.05mg sodium azide | |
O95433 | |
Ahsa1 | |
E. coli-derived human AHA1 recombinant protein (Position: N21-F338). | |
100 μg | |
Primary | |
Human, Monkey | |
Antibody | |
IgG |
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