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Aiolos Monoclonal Antibody (8B2), Active Motif™
SDP

Catalog No. 501992765
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50-199-2765 10 μg
50-199-2764 100 μg
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Catalog No. 50-199-2765 Supplier Active Motif Supplier No. 39658
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Description

Mouse Monoclonal Antibody

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Specifications

Antigen Aiolos
Applications ChIP Assay, Western Blot
Classification Monoclonal
Clone 8B2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Ikzf3
Gene Accession No. O08900
Gene Alias 5830411O07Rik; AIO; AIOLOS; BOS_19124; IKAROS family zinc finger 3; IKAROS family zinc finger 3 (Aiolos); Ikaros family zinc finger protein 3; Ikzf3; LOC100356392; Zfpn1a3; zinc finger DNA binding protein Aiolos; Zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); ZNFN1A3
Gene Symbols Ikzf3
Host Species Mouse
Immunogen This Aiolos antibody was raised against the N-terminal half of mouse Aiolos protein.
Purification Method Protein G
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22780
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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