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AIRE Mouse anti-Human, Porcine, Clone: 1A3C3, Proteintech
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Catalog No. 501736695 Shop All Proteintech Group Inc Products
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150 μL
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50-173-6695 150 μL
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Catalog No. 50-173-6695 Supplier Proteintech Group Inc Supplier No. 662621IG150UL
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Description

Mouse Monoclonal Antibody

The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Specifications

Antigen AIRE
Applications Western Blot
Classification Monoclonal
Clone 1A3C3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AIRE
Gene Accession No. O43918
Gene Alias AIRE, AIRE1, APECED, APECED protein, APS1, APSI, autoimmune regulator, PGA1
Gene Symbols AIRE
Host Species Mouse
Immunogen AIRE Fusion Protein Ag19103
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100621659, 326
Target Species Human, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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