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Invitrogen™ AKAP12 Polyclonal Antibody
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Catalog No. PIPA5114833
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PIPA5114833 100 μL
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Catalog No. PIPA5114833 Supplier Invitrogen™ Supplier No. PA5114833
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total AKAP12.

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AKAP12
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene AKAP12
Gene Accession No. Q02952
Gene Alias A kinase (PRKA) anchor protein (gravin) 12; A kinase (PRKA) anchor protein 12; AI317366; AKAP 250; AKAP12; AKAP-12; AKAP12A; AKAP12B; AKAP12G; AKAP250; A-kinase anchor protein 12; A-kinase anchor protein 250 kDa; A-kinase anchor protein, 250kDa; A-kinase anchoring protein 12; Gag12; gercelin; germ cell lineage protein gercelin; Gravin; kinase scaffold protein gravin; Myasthenia gravis autoantigen; myasthenia gravis autoantigen gravin; Srcs5; Src-Suppressed C Kinase Substrate; SSeCKS; SSeCKS, Gravin, AKAP250; testis specific gene A12; Tsga12; v-src suppressed transcript 5
Gene Symbols AKAP12
Host Species Rabbit
Immunogen A synthesized peptide derived from human AKAP12(Accession Q02952), corresponding to amino acid residues G1749-S1782.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9590
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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