Invitrogen™ AKAP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538015

Catalog No. PIPA538015

Description

A recommended positive control is human testis tissue lysate. At least three isoforms are known to exist; this antibody will detect the two longest isoforms.

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm. It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways. AKAP4 has also been postulated to be a potential biomarker for breast cancer.

Specifications

• Antigen: AKAP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AKAP4
• Gene Alias: 75 kDa fibrous sheath protein; A kinase (PRKA) anchor protein 4; AKAP 82; AKAP4; AKAP-4; akap4 {ECO:0000312; AKAP82; A-kinase anchor protein 4; A-kinase anchor protein 82 kDa; A-kinase anchoring protein 4; cancer/testis antigen 99; CT99; Fsc1; hAKAP82; HI; major sperm fibrous sheath protein; mAKAP82; p82; PRKA4; protein kinase A anchoring protein 4; protein kinase A-anchoring protein 4; RGD:620828}; testis-specific gene HI
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8852
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q5JQC9
• Gene Symbols: AKAP4
• Immunogen: 17 amino acid peptide near the amino terminus of human AKAP4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG