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TARGETMOL CHEMICALS INC AKB-6899 5MG

Supplier: TARGETMOL CHEMICALS INC T29797

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2(alpha) which induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth. purity: 98%
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