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Invitrogen™ AKR1C1 Polyclonal Antibody
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Catalog No. PIPA584776
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PIPA584776 100 μL
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Catalog No. PIPA584776 Supplier Invitrogen™ Supplier No. PA584776
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Rabbit Polyclonal Antibody

Immunogen sequence: EPWVDPNSPV LLEDPVLCAL AKKHK Highest antigen sequence indentity to the following orthologs: Mouse - 72%, Rat - 72%.

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AKR1C1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene AKR1C1
Gene Accession No. Q04828
Gene Alias 17-beta-HSD 5; 17HSD type 5; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); 20-ALPHA-HSD; 20-alpha-hydroxysteroid dehydrogenase; 2-ALPHA-HSD; 3alpha-HSD; Akr1c1; Akr1c6; aldo-keto reductase C; aldo-keto reductase family 1 member C1; aldo-keto reductase family 1, member C1; aldo-keto reductase family 1, member C1 (aldehyde reductase); aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C6; C9; chlordecone reductase homolog HAKRC; DD1; DD1/DD2; DDH; DDH1; dihydrodiol dehydrogenase 1; dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase; dihydrodiol dehydrogenase isoform DD1; estradiol 17 beta-dehydrogenase 5; estradiol 17-beta-dehydrogenase (A-specific); H-37; HAKRC; HBAB; hepatic dihydrodiol dehydrogenase; high-affinity hepatic bile acid-binding protein; Hsd17b5; hydroxysteroid 17-beta dehydrogenase 5; indanol dehydrogenase; MBAB; RP11-69D4.1; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type 5 17beta-hydroxysteroid dehydrogenase; type II 3-alpha-hydroxysteroid dehydrogenase
Gene Symbols AKR1C1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human AKR1C1. Recombinant protein control fragment (Product #RP-105445).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1645
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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