AKT1 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI4D6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF504230

Catalog No. 50-166-2729

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB.

Specifications

• Antigen: AKT1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: AKT1
• Gene Alias: AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11651, 207, 24185, 490878
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4D6
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P31749, P31750, P47196
• Gene Symbols: Akt1
• Immunogen: Full length human recombit protein of human AKT1 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1