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AktS1/PRAS40 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501559522
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50-155-9522 20 μL
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Catalog No. 50-155-9522 Supplier Bethyl Laboratories, Inc Supplier No. A301201AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse

The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.

Specifications

Antigen AktS1/PRAS40
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene AKT1S1
Gene Accession No. Q96B36
Gene Alias 40 kDa proline-rich AKT substrate; OTTHUMP00000196756; OTTHUMP00000196760; proline-rich AKT1 substrate 1; proline-rich Akt substrate, 40 kDa
Gene Symbols AKT1S1
Host Species Rabbit
Immunogen Between 195 and 245
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84335
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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