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Invitrogen™ alanyl-tRNA Synthetase Polyclonal Antibody
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Catalog No. PIPA583712
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100 μL
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PIPA583712 100 μL
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Catalog No. PIPA583712 Supplier Invitrogen™ Supplier No. PA583712
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EFTVKNAQVR GGYVLHIGTI YGDLKVGDQV WLFIDEPRRR PIMSNHTATH ILNFALRSVL GEADQKGSLV APDRLRFDFT AKGAMSTQQI KKAEEIANEM IEAAKAVYTQ DCP Highest antigen sequence indentity to the following orthologs: Mouse - 95%, Rat - 90%.

The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E. coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
TRUSTED_SUSTAINABILITY

Specifications

Antigen alanyl-tRNA Synthetase
Applications Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene AARS1
Gene Accession No. P49588
Gene Alias Aars; AI316495; alanine tRNA ligase 1, cytoplasmic; alanine--tRNA ligase, cytoplasmic; alanine--tRNA ligase, cytoplasmic {ECO:0000255; Alanyl-tRNA synthetase; alanyl-tRNA synthetase {ECO:0000255; alanyl-tRNA synthetase, cytoplasmic; alaRS; alaRS {ECO:0000255; C76919; CMT2N; EIEE29; HAMAP-Rule:MF_03133}; Protein sticky; Renal carcinoma antigen NY-REN-42; sti
Gene Symbols AARS1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human AARS. Recombinant protein control fragment (Product #RP-104790).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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