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Invitrogen™ ALDH1A1 Polyclonal Antibody
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Catalog No. PIPA595937
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PIPA595937 100 μL
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Catalog No. PIPA595937 Supplier Invitrogen™ Supplier No. PA595937
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Description

Rabbit Polyclonal Antibody

Positive Samples: A-549, HT-29, K-562, Mouse liver, Mouse lung, Rat lung; Cellular Location: Cytoplasm Immunogen sequence: KYILGNPLTP GVTQGPQ.

ALDH1A1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALDH1A1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.04 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ALDH1A1
Gene Accession No. P00352, P24549, P51647
Gene Alias acetaldehyde dehydrogenase 1; Ahd2; Ahd-2; alcohol dehydrogenase family 1, subfamily A1; alcohol dehydrogenase family 1, subfamily A2; ALDC; aldehyde dehydrogenase 1 family member A1; aldehyde dehydrogenase 1 family, member A1; Aldehyde dehydrogenase 1 soluble; aldehyde dehydrogenase 1, liver cytosolic (class 1); aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase 1, subfamily A1; aldehyde dehydrogenase 1A1; aldehyde dehydrogenase 2; aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase family 1, member A1; aldehyde dehydrogenase family 1, subfamily A1; aldehyde dehydrogenase, cytosolic; aldehyde dehydrogenase, liver cytosolic; Aldh; ALDH class 1; Aldh1; ALDH11; ALDH1A1; Aldh1a2; Aldh2; ALDH-E1; ALHDII; E1; epididymis luminal protein 12; epididymis luminal protein 9; epididymis secretory sperm binding protein Li 53e; epididymis secretory sperm binding protein Li53e; HEL12; HEL-9; HEL-S-53e; MGC2318; PUMB1; RALDH 1; ralDH1; Retinal dehydrogenase 1; retinaldehyde dehydrogenase 1
Gene Symbols ALDH1A1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 301-400 of human ALDH1A1 (NP_0006802).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11668, 216, 24188
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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