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Invitrogen™ ALDH2 Monoclonal Antibody (4G6A3)
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Catalog No. PIMA517029
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100 μg
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Catalog No. Quantity
PIMA517029 100 μg
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Catalog No. PIMA517029 Supplier Invitrogen™ Supplier No. MA517029
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Description

Mouse Monoclonal Antibody

MA5-17029 targets ALDH2 in FACS, ICC, IHC, IF and WB applications and shows reactivity with Human, Mouse, and Rat samples. The MA5-17029 immunogen is purified recombinant fragment of human ALDH2 (amino acids: 317-517) expressed in E. Coli. MA5-17029 detects ALDH2 which has a predicted molecular weight of approximately 56.3kDa.

ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALDH2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4G6A3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Aldh2
Gene Accession No. P05091, P11884, P47738
Gene Alias acetaldehyde dehydrogenase 2; Ahd1; Ahd-1; Ahd5; Ahd-5; AHD-M1; aldehyde dehydrogenase 2 family (mitochondrial); aldehyde dehydrogenase 2, mitochondrial; aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH1; ALDH2; ALDH-E2; ALDHI; ALDM; EC 1.2.1.3; liver mitochondrial ALDH; MGC1806; mitochondrial aldehyde dehydrogenase; nucleus-encoded mitochondrial aldehyde dehydrogenase 2
Gene Symbols Aldh2
Host Species Mouse
Immunogen Purified recombinant fragment of human ALDH2 (amino acids: 317-517) expressed in E. Coli.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11669, 217, 29539
Target Species Human, Mouse, Rat, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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