Invitrogen™ Aldolase A Recombinant Rabbit Monoclonal Antibody (21H7L6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 702729

Catalog No. 70-272-9

Description

This antibody is predicted to react with Monkey, Cat, Rabbit Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.

Specifications

• Antigen: Aldolase A
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P04075, P05064, P05065
• Gene Symbols: ALDOA
• Immunogen: Peptides corresponding to human Aldolase A [1) aa341-aa360 2) aa84-aa103].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Clone: 21H7L6
• Conjugate: Unconjugated
• Gene: ALDOA
• Gene Alias: ALDA; Aldo1; Aldo-1; ALDOA; Aldolase 1; aldolase 1, A isoform; aldolase A; aldolase A, fructose-bisphosphate; aldolase, fructose-bisphosphate A; epididymis secretory sperm binding protein Li 87p; fructose-1,6-bisphosphate triosephosphate-lyase; fructose-bisphosphate aldolase A; GSD12; HEL-S-87p; Lung cancer antigen NY-LU-1; muscle-type aldolase; RNALDOG5; unnamed protein product
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11674, 226, 24189
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid