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Invitrogen™ Aldolase B Polyclonal Antibody
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Catalog No. PIPA5116491
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PIPA5116491 100 μL
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Catalog No. PIPA5116491 Supplier Invitrogen™ Supplier No. PA5116491
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Description

Rabbit Polyclonal Antibody

Positive controls: SH-SY5Y lysate, human liver tissue lysate, mouse liver tissue lysate, mouse kidney tissue lysate, rat kidney tissue, human liver tissue, human kidney tissue, mouse small intestine tissue, SH-SY5Y.

Fructose-1,6-bisphosphate aldolase is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aldolase B
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Aldob
Gene Accession No. P00884, P05062, Q91Y97
Gene Alias ALDB; Aldo2; Aldo-2; ALDOB; Aldolase 2; aldolase 2, B isoform; Aldolase B fructose-biphosphate; Aldolase B, fructose-biphosphate; aldolase B, fructose-bisphosphatase; aldolase B, fructose-bisphosphate; aldolase, fructose-bisphosphate B; BC016435; Fructose-bisphosphate aldolase B; LIV10; Liver-type aldolase
Gene Symbols Aldob
Host Species Rabbit
Immunogen Recombinant protein within Human Aldolase B aa 1-189.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 229, 230163, 24190
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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