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  6. Invitrogen™ alpha-1 Antitrypsin Monoclonal Antibody (1AT11-210.1), Invitrogen™

Invitrogen™ alpha-1 Antitrypsin Monoclonal Antibody (1AT11-210.1), Invitrogen™

Catalog No. PIMA546034
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PIMA546034 100 μg
01-671-579 500 μg
PIMA546019 1 mg
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Catalog No. PIMA546034 Supplier Invitrogen™ Supplier No. MA546034
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Description

Mouse Monoclonal Antibody

MA1-10626 detects alpha-1 Antitrypsin from human samples. MA1-10626 does not cross react with alpha-1-antichymotrysin. MA1-10626 has been successfully used in ELISA applications. The MA1-10626 immunogen is purified human serum alpha-1 Antitrypsin.

Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma. Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn. Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation. Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen alpha-1 Antitrypsin
Applications ELISA
Classification Monoclonal
Clone 1AT11-210.1
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene SERPINA1
Gene Accession No. P01009
Gene Alias a-1 AT; A1A; a1-antitrypsin; A1AT; AAT; Aat2; Aat-2; alpha 1 antitrypsin; alpha-1 antitrypsin; alpha-1 protease inhibitor; Alpha-1 protease inhibitor 1; alpha-1-antiproteinase; Alpha-1-antitrypsin; alpha-1-antitrypsin (protease inhibitor); alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 2; alpha-1-antitrypsin null; alpha1AT; alpha-1-protease inhibitor; alpha-1-proteinase inhibitor; Digestive Zymogen; Dom1; MGC23330; MGC9222; PI; PI1; PRO0684; PRO2209; PRO2275; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1); Protease Serine 1; serine (or cysteine) peptidase inhibitor, clade A, member 1A; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1a; Serine Protease 1; serine protease inhibitor 1-1; Serine protease inhibitor A1a; serine protease inhibitor alpha 1; serine proteinase inhibitor, clade A, member 1; serpin A1; Serpin A1a; serpin family A member 1; serpin peptidase inhibitor clade A member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; SERPINA1; Serpina1a; Short peptide from AAT; SPAAT; Spi1; Spi1-1; Spi1-3; TRP1; TRY1
Gene Symbols SERPINA1
Host Species Mouse
Immunogen Purified human serum alpha-1 Antitrypsin.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5265
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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