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Invitrogen™ alpha-2a Adrenergic Receptor Polyclonal Antibody
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Catalog No. PA1048 Shop All Thermo Scientific Products
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PA1048 100 μL
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Catalog No. PA1048 Supplier Invitrogen™ Supplier No. PA1048
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Description

Rabbit Polyclonal Antibody

PA1-048 detects alpha-2A adrenergic receptor (A2AAR) from human, rat and mouse tissues. PA1-048 has been successfully used in Western blot and immunohistochemistry procedures. By Western blot, this antibody detects an ~45 kDa protein representing A2AAR from mouse kidney membrane preparations. The PA1-048 immunogen is a synthetic peptide corressponding to residues R(218) I Y Q I A K R R T R V P P S R R G(235) of the 3rd intracellular loop of human A2AAR. This sequence is completely conserved between human, mouse, rat, and porcine A2AAR.

Alpha-2-adrenergic receptors (ADRA2A) are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. ADRA2A mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G protein. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system.
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Specifications

Antigen alpha-2a Adrenergic Receptor
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 1 mg/mL BSA and 0.05% sodium azide
Gene Adra2a
Gene Accession No. P08913, P22909, Q01338
Gene Alias ADRA2; Adra-2; ADRA2A; Adra-2a; ADRA2R; ADRAR; adrenergic receptor, alpha 2a; adrenergic, alpha-2A-, receptor; adrenoceptor alpha 2A; alpha(2A)AR; alpha-2 adrenergic receptor subtype C10; alpha2A; alpha-2A adrenergic receptor; Alpha-2A adrenoceptor; alpha-2A adrenoreceptor; alpha2A-adrenergic receptor; ALPHA2AAR; alpha-2AAR; alpha2A-AR; alpha-2AAR subtype C10; alpha-2-adrenergic receptor, platelet type; alpha2-C10; alpha-2D adrenergic receptor; AW122659; CA2-47; OTTHUMP00000058849; RATRG20; RG20; subtype alpha2-C10; ZNF32
Gene Symbols Adra2a
Host Species Rabbit
Immunogen Synthetic peptide corressponding to residues R(218) I Y Q I A K R R T R V P P S R R G(235) of the 3rd intracellular loop of human A2AAR.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11551, 150, 25083
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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