Invitrogen™ alpha-Cardiac Actin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521396

Catalog No. PIPA521396

Description

Recommended positive controls: Jurkat , Raji, K562, THP-1, NIH-3T3, JC, BCL-1, Rat muscle, PC-12, Rat2. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (99%), Pig (100%), Chicken (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ACTC1 are part of actins, which are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Specifications

• Antigen: alpha-Cardiac Actin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACTC1
• Gene Alias: ACTC; Actc1; Actc-1; actin alpha cardiac; actin alpha cardiac 1; actin alpha cardiac muscle 1; actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle; actin, alpha, cardiac muscle 1; alpha-actin cardiac; alphac-actin; alpha-cardiac actin; ASD5; B-actin; cardiac muscle alpha actin 1; CMD1R; CMH11; LVNC4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11464, 29275, 70
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.39 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P68032, P68033, P68035
• Gene Symbols: ACTC1
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 99 and 354 (P68032) of alpha Actin (cardiac muscle).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov