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Cellular Engineering Technologies Cryopreserved vial of induced pluripotent stem cells from a single male donor with Alzheimer's Presenilin-1 Mutation (500,000 cells)
Supplier: Cellular Engineering Technologies CR1008500
Cell line was derived from a single male with Alzheimer's disease, with onset occurring at the age of 45. The donor cells were collected via skin biopsy of the forearm antemortem. The cell morphology is fibroblast-like. Vial contains 500,000 cells. Shipped with dry ice.Mutations in the PSEN1 gene, encoding presenilin-1 (PS1), are the most common common cause of familial Alzheimer's disease (FAD). PS1 is the catalytic subunit of y-secretase, an intramembranous protease that cleaves various type 1 transmembrane proteins, notably the amyloid precursor protein (APP) and Notch.Vial contains approximately 500,000 cells. Shipped with dry ice.
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