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Cayman Chemical AM251, 183232-66-8, 10 mg
SDP

Supplier:  Cayman Chemical 7167010

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A CB1 antagonist and CB2 inverse agonist; Kis = 7.5 and 2,290 nM for CB1 and CB2 from rat forebrain and mouse spleen, respectively; agonist at GPR55 (EC50 = 39 nM); potentiates GABAA currents (EC50 = 0.4 µM); prevents TGF-β1-induced EMT in HK-2 renal tubule epithelial cells independent of CB receptors or GPR55; halts the cell cycle and induces apoptosis in A375 human melanoma cells; reduces antidepressant-like behavior and decreases fasting-induced hyperphagia in mice

Catalog No. NC9004721


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