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Tocris Bioscience™ Ambrisentan
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Catalog No. 582850
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective ETA antagonist

Ambrisentan is a selective endothelin receptor ETA antagonist. Displays approximately 200-fold selectivity for ETA over ETB (Ki values are 1 nM and 195 nM for respectively). Prevents endothelin-induced sudden death in rats.

Specifications

Chemical Name or Material (αS)-α-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoic acid
CAS 177036-94-1
Quantity 50 mg
Molecular Formula C22H22N2O4
Purity 99%
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