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Invitrogen™ AMER2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA558794
Description
Immunogen sequence: VDDTYLQEFW DMLSQTEEQG PEPQEGAAKV AAALETKVVP ETPKDTRCVE AAKDASSVKR RRLNRIPIEP HPKEEPKHPE KEQQE Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.
Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.
Specifications
AMER2 | |
Polyclonal | |
Unconjugated | |
AMER2 | |
2600011E07Rik; AMER2; APC membrane recruitment 2; APC membrane recruitment protein 2; Fam123a; family with sequence similarity 123, member A; family with sequence similarity 123A; protein FAM123A; RGD1559605 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
219287 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.15 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q8N7J2 | |
AMER2 | |
Recombinant protein corresponding to Human AMER2. Recombinant protein control fragment (Product #RP-97993). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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