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Tocris Bioscience™ AMG 837 hemicalcium salt
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Catalog No. 608250
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60-825-0 50 mg
60-821-0 10 mg
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Catalog No. 60-825-0 Supplier Tocris Bioscience™ Supplier No. 6082/50
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Description

Potent free fatty acid receptor 1 (FFA1/GPR40) partial agonist

AMG 837 hemicalcium salt is a potent free fatty acid receptor 1 (FFA1/GPR40) partial agonist (EC50 values are 13.5, 22.6 and 31.7 nM at human, mouse and rat receptors, respectively). Interacts allosterically with full FFA1 agonist Docosahexaenoic acid (Cat. No. 3687). Potentiates glucose-dependent stimulation of insulin in vivo. Antidiabetic.

Specifications

Chemical Name or Material AMG 837 hemicalcium salt
CAS 1291087-14-3
Synonym (βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid hemicalcium salt
Quantity 50 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C26H20F3O3.?Ca
Formula Weight 457.47
Physical Form Solid
Color White
Product Type Bioactive Small Molecule
Purity >98%
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For Research Use Only.

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