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Invitrogen™ AMID Polyclonal Antibody
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Catalog No. p-7184246
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100 μL
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PIPA5110968 100 μL
PIPA5111150 100 μL
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Catalog No. PIPA5110968 Supplier Invitrogen™ Supplier No. PA5110968
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NLVILCTGIK INSSAYRKAF ESRLASSGAL RVNEHLQVEG HSNVYAIGDC ADVRTPKMAY LAGLHANIAV ANIVNSVKQR PLQAYKPGAL TFLLSMGRND GVGQISGFYV GRLMVRLTKS RDLFVSTSWK TM Highest antigen sequence indentity to the following orthologs: Rat - 86%, Mouse - 86%.

The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AMID
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene AIFM2
Gene Accession No. Q9BRQ8
Gene Alias 5430437E11Rik; AIFM2; Amid; apoptosis inducing factor, mitochondria associated 2; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated 2; apoptosis-inducing factor, mitochondrion-associated, 2; apoptosis-inducing factor-like mitchondrion-associated inducer of death; apoptosis-inducing factor-like mitochondrion-associated inducer of death; D730001I10Rik; MBP2; MBPH; MGC126662; MGC141971; p53-responsive gene 3 protein; PRG3; RP11-367H5.2
Gene Symbols AIFM2
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human AMID. Recombinant protein control fragment (Product #RP-105802).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84883
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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