Amiodarone hydrochloride

Description

A non-selective ion channel blocker; also an antiarrhythmic agent | CAS: 19774-82-4 | C25H30ClI2NO3 | 681.778 g/mol

Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.

Solubility
Soluble in chloroform, methanol.

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat. Store in refrigerator.

Specifications

Chemical Identifiers

• CAS: 19774-82-4
• Molecular Formula: C25H30ClI2NO3
• Molecular Weight (g/mol): 681.778
• MDL Number: MFCD00069204
• InChI Key: ITPDYQOUSLNIHG-UHFFFAOYSA-N
• Synonym: amiodarone hydrochloride, amiodarone hcl, amiodar, nexterone, pacerone, amiodaronum hydrochloride, ritmocardyl, rythmarone, angoron
• PubChem CID: 441325
• IUPAC Name: (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone;hydrochloride
• SMILES: CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I.Cl

• Melting Point: 156°C to 163°C
• Color: White
• Quantity: 25 g
• Merck Index: 14,482
• Solubility Information: Soluble in chloroform,methanol.
• Formula Weight: 681.77
• Physical Form: Powder
• Chemical Name or Material: Amiodarone hydrochloride

Safety and Handling

Hazard Category	H312+H332-H361d-H373
Precautionary Statement	P201-P202-P260-P271-P281-P302+P352-P304+P340-P308+P313-P312-P363-P501c
EINECSNumber	243-293-2
RTECSNumber	OB1361000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only