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Tocris Bioscience™ Amisulpride
GREENER_CHOICE

Selective D2 and D3 antagonist; atypical antipsychotic

Supplier:  Tocris Bioscience™ 2132/50

Catalog No. 21-325-0


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Description

Description

Amisulpride is a potent, selective dopamine D2 and D3 receptor antagonist. Ki values are 2.8 and 3.2 nM respectively for human D2 and D3 and > 1000 nM for human D1, D4 and D5 receptors. Shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic D2/D3 receptors at higher doses. Preferentially interacts with limbic D2-like receptors in vivo. Atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride.
Specifications

Specifications

>98%
50 mg
369.48
DAN 2163
Amisulpride
Amisulpride
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